Ionic Liquid Modified SPION@Chitosan as a Novel and Reusable Superparamagnetic Catalyst for Green One-Pot Synthesis of Pyrido[2,3-d]pyrimidine-dione Derivatives in Water

In this paper, the chitosan-functionalized ionic liquid is modified with superparamagnetic iron oxide nanoparticles to form a novel and reusable catalyst (SPION@CS-IL), which was carried out using an ultrasonic promoted approach. Transmission electron microscopy (TEM), vibrating-sample magnetometer (VSM), energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FT-IR), powder diffraction (XRD), thermogravimetric analysis (TGA) are some of techniques that used fully characterize SPION@CS-IL. The created were discovered be heterogeneous for environmentally friendly one-pot synthesis pyrido[2,3-d]pyrimidine derivatives simple three-component reaction approach involving thiobarbituric acid, 4-hydroxy coumarin, various aromatic aldehydes. method studied by performing under irradiation, while “green” method, it uses water as solvent. isolated yields synthesized products very advantageous. has outstanding reusability easily removed from via filtration (5 runs). Short times, low loadings, nanocatalyst’s capacity recycled five absence harmful chemical reagents all significant benefits benign process.